Pharmacy Freak GPAT

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1. The required amount of adjusting substance required to make a hypotonic solution isotonic is given by the (W = adjusting substance, a = freezing point depression of unadjusted solution and b = freezing point depression of water): a - 0.52 W = ?

A. 4

B. 2

C. 1

D. 3

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2. Match List I with List II

List I	List II
A. Penicillin	I. Single cell protein
B. Pruteen	II. Ion exchange chromatography for recovery
C. Streptomycin	III. Primary metabolite
D. Amino acids	IV. Phenyl acetic acid as precursor

Options:

(a) (A)-(II); (B)-(I): (C)-(IV); (D)-(III)
(b) (A)-(IV); (B)-(I): (C)-(II); (D)-(III)
(c) (A)-(III); (B)-(II): (C)-(I); (D)-(IV)
(d) (A)-(II); (B)-(III): (C)-(IV); (D)-(I)

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Match List I with List II. Choose the correct answer from the options given below:

3. List I	List II
A. Triethanolamine oleate B. N-cetyl N-ethyl morpholinium C. Polyoxyethylene sorbitan mono D. Gelatin	I. Surface-active agent (non-ionic) II. Hydrophilic colloid III. Surface-active agent (anionic) IV. w/o emulsifier (HLB = 4.3) V. Surface-active agent (cationic)

Options:

(a) (A)-(II); (B)-(IV); (C)-(V); (D)-(III)
(b) (A)-(III); (B)-(V); (C)-(I); (D)-(II)
(c) (A)-(V); (B)-(IV); (C)-(II); (D)-(III)
(d) (A)-(IV); (B)-(III); (C)-(V); (D)-(I)

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4. Match List I with List II

List I	List II
A. Gasket	I. Links the dip tube and the stem and the actuator
B. Spring	II. Prevents the leakage
C. mounting cup	III. Holds the Gasket in place
D. Housing	IV. Holds the valve in place

Options:

(a) (A)-(III); (B)-(II); (C)-(IV); (D)-(I)
(b) (A)-(II); (B)-(III); (C)-(IV); (D)-(I)
(c) (A)-(IV); (B)-(I); (C)-(II); (D)-(III)
(d) (A)-(III); (B)-(I); (C)-(IV); (D)-(II)

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5. One of the following is correct match or mechanisms. Select it.

A. Methotrexate-Inhibition of Purine synthesis, Vinca alkaloids-Inhibition of Microtubules, Bleomycin-DNA damage, 5-fluoro Uracil-inhibition of 2- deoxythymidylate

B. Methotrexate-DNA damage, Vinca alkaloids-Inhibition of microtubules, Bleomycin-Inhibition of 2-deoxythymidylate, 5-Fluoro Uracil-RNA damage

C. Methotrexate-Inhibition of microtubules, Vinca alkaloids -Inhibition of Purine synthesis, Bleomycin-Inhibition of RNA, 5-Fluoro Uracil-DNA damage

D. Methotrexate-DNA damage, Vinca alkaloids-RNA damage, Bleomycin- Inhibition of Purine synthesis, 5- Fluoro Uracil-Inhibition of 2- deoxythymidylate

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6. One of the following match is correct choose it :

A. M1 Acetylcholine receptors confined to brain M2 Acetylcholine receptors neural M3 Acetylcholine receptors are cardiac M4 Acetylcholine receptors glandular

B. M1 Acetylcholine receptors neural M2 Acetylcholine receptors confined to brain M3 Acetylcholine receptors are cardiac M4 Acetylcholine receptors glandular

C. M1 Acetylcholine receptors neural M2 Acetylcholine receptors cardiac M3 Acetylcholine receptors are confined to glandular M4 Acetylcholine receptors confined to brain

D. M1 Acetylcholine receptors glandular M2 Acetylcholine receptors neural M3 Acetylcholine receptors are confined to brain M4 Acetylcholine receptors cardiac

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7. Match List I with List II. Choose the correct answer from the options given below:

List I	List II
A. Zolpidem B. Zaleplon C. Zopiclone D. Triazolam	I. Cyclopyrrolone II. Benzodiazepine III. Imidazopyridine IV. Pyrazolopyrimidine

Options:

(a) (A)-(IV); (B)-(III); (C)-(II); (D)-(I)
(b) (A)-(II); (B)-(IV); (C)-(III); (D)-(I)
(c) (A)-(III); (B)-(IV); (C)-(I); (D)-(II)
(d) (A)-(I); (B)-(III); (C)-(IV); (D)-(II)

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The below structure represent the drug:

A. Isoprenaline

B. Norepinephrine

C. Salbutamol

D. Amphetamine

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9. Match the photopharmaceutical with the plant species from

List I	List II
	which they are produced :
A. Cardinolides	I. Ruta graveolens
B. Rutin	II. Catharanthus roseus
C. Ajamalicine	III. Papaver somnifera
D. Codeine	IV. Digitalis lanata

Options:

(a) (A)-(IV); (B)-(I): (C)- (II); (D)-(III)
(b) (A)-(I); (B)-(III): (C)-(II); (D)-(IV)
(c) (A)-(III); (B)-(I); (C)-(III); (D)-(IV)
(d) (A)-(II): (B)-(IV); (C)- (I); (D)-(III)

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10. Match List I with List II

List I	List II
A. Vibrations in skeletal muscles of larynx	I. Facial contractions
B. Involuntary contraction of skeletal muscles that is regulated by the brain	II. Regulate voice
C. Contraction of skeletal muscles in the legs	III. Shivering
D. Pull of skeletal muscles on attachments to skin of face	IV. Assists return of blood to the heart
	V. Causes facial expressions

Options:

(a) (A)-(II); (B)-(Ill); (C)-(IV); (D)-(I)
(b) (A)-(III); (B)-(IV); (C)-(I); (D)-(V)
(c) (A)-(II); (B)-(III); (C)-(IV); (D)-(V)
(d) (A)-(III); (B)-(IV); (C)-(V); (D)-(I)

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11. Match List I with List II. Choose the correct answer from the options given below:

List I	List II
A. Type 1 B. Type 5 C. USP App 6 D. USP App 7	I. Reciprocating holder II. Paddle overdisk III. Basket type IV. Cylinder apparatus

Options:

(a) (A)-(III); (B)-(II); (C)-(IV); (D)-(I)
(b) (A)-(IV); (B)-(I); (C)-(II); (D)-(III)
(c) (A)-(II); (B)-(III); (C)-(I); (D)-(II)
(d) (A)-(I); (B)-(II); (C)-(III); (D)-(IV)

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